Persisting Pain? What Doctors Will Want to Know


By Staff Reports

(DGIwire) – Pain is an inevitable part of life—many active people can break bones, pull tendons, sustain sprains, strain muscles and damage tissue—but that doesn’t mean the pain should linger too long after the original injury. In fact, the president of the American Academy of Pain Medicine, explained to WebMD that acute pain is good because it lets the body know when an injury has been sustained, but that the pain should stop when the injury heals. For those who experience persistent pain after suffering an injury, it could be worth scheduling an appointment and discussing the pain further with a doctor or a pain specialist.

It’s important not to let any persistent pain go unreported. This is especially so for women with chronic pain. According to The Wall Street Journal, women are more prone to chronic painful conditions than men and are more likely to experience greater pain than men who suffer from the same conditions. Amy Niles, president of The National Women’s Health Resource Center, reports that women with pain are likely to be undertreated, perhaps because they have trouble convincing doctors of the severity of their pain.

According to the Mayo Clinic, patients with persistent pain may want to prepare for an appointment by anticipating the questions their doctor will ask, such as:

  1. Is the pain caused by a recent accident, illness or injury, such as trauma to limbs, a heart attack or an infection?
  2. Has there been a recent surgery?
  3. When did the pain first begin?
  4. Can you describe the pain (aching, throbbing, burning, stabbing, etc.)?
  5. How long have the symptoms been present?
  6. Is the pain occasional or continuous?
  7. Does anything seem to improve or worsen the symptoms?
  8. Have similar symptoms been experienced after past injuries?

One possible diagnosis a doctor may offer to explain the persistent pain is complex regional pain syndrome (CRPS). CRPS can strike anyone but affects women more commonly than men, reports the National Institute for Neurological Disorders and Stroke (NINDS). Signs and symptoms can include continuous burning or throbbing pain, usually in an arm, leg, hand or foot; sensitivity (in the place of the originating injury/trauma) to touch or cold; swelling of the painful area; changes in skin temperature, color or texture; and stiffness and spasms, according to NINDS.

Although there is currently no medication approved for the treatment of CRPS in the United States or the European Union, it is vital that patients with the condition receive an accurate diagnosis as soon as possible so that various approaches to treatment can be initiated. New innovative approaches specifically targeting CRPS are now being developed.

Doctor showing his notes to his patientAxsome Therapeutics, Inc., a clinical-stage biopharmaceutical company is developing novel therapies for the management of central nervous system disorders. “When speaking with their doctors, patients may also want to ask about any ongoing trials that could be a good fit. A clinical study, called CREATE-1, is evaluating our experimental medication AXS-02 for the treatment of chronic pain caused by CRPS. Patients are currently being enrolled for this trial across the U.S., Canada, the U.K. and Australia,” says Randall Kaye, M.D., Chief Medical Officer of Axsome Therapeutics, Inc. “AXS-02 is not yet approved, but it has been granted Fast Track and Orphan Drug Designation by the U.S. Food and Drug Administration and Orphan Medicinal Product Designation.”

Anyone who suspects they have CRPS and is interested in learning if they qualify for the study should visit

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